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The Kirby-Bauer disk diffusion test is routinely used to determine:

A. The susceptibility of a given bacterial strain to a battery of antimicrobial drugs
B. How rapidly a drug will spread inside the body to aid in determining the proper dose
C. The lowest concentration of a specific drug needed to prevent the growth of a given bacterial strain in vitro
D. The lowest concentration of a drug that kills 99.9% of cells of a given bacterial strain in vitro

Answer :

The Kirby-Bauer disc diffusion test is routinely used to determine a) the susceptibility of a given bacterial strain to a battery of antimicrobial drugs.

The is a simple and rapid method for determining how susceptible a bacterial pathogen is to various antimicrobial drugs. In this test, a Mueller-Hinton agar plate is inoculated with the bacterial strain and then small disks impregnated with different antimicrobial drugs are placed on the plate.

As the bacteria grow, they interact with the drugs, forming clear zones of inhibition where the bacteria are unable to grow. The diameters of these zones are measured and compared to standard reference values to determine if the bacteria are susceptible or resistant to the drugs.

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