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Answer :
Final answer:
To order a steady state drug level, we need to consider the half-life of the drug and the dosing schedule. A reasonable time to order a steady state drug level would be after 3-4 half-lives, which is approximately 24-32 hours of administration.
Explanation:
To order a steady state drug level, we need to consider the half-life of the drug and the dosing schedule. In this case, the drug has a half-life of 8 hours and is dosed twice daily. A steady state drug level is achieved when the rate of drug administration equals the rate of drug elimination. After multiple half-lives, approximately 94% of the drug is eliminated. So, a reasonable time to order a steady state drug level would be after 3-4 half-lives, which is approximately 24-32 hours of administration.
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