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Which of the following correctly matches the dosage levels of sedative-hypnotics with their associated effects?

A) Low dosage: GAD and OCD treatment; Low-medium dosage: sedation; Medium-high dosage: sleep onset; High dosage: general anesthesia

B) Low dosage: sedation; Low-medium dosage: hypnosis; Medium-high dosage: sleep onset; High dosage: general anesthesia

C) Low dosage: anti-anxiety (GAD, OCD); Low-medium dosage: sedation; Medium-high dosage: hypnosis; High dosage: general anesthesia

D) Low dosage: sleep onset; Low-medium dosage: sedation; Medium-high dosage: anti-anxiety (GAD, OCD); High dosage: general anesthesia

Answer :

Final answer:

The correct match for dosage levels of sedative-hypnotics with their effects is: Low dosage for anti-anxiety treatment, low-medium dosage for sedation, medium-high dosage for hypnosis/sleep onset, and high dosage for general anesthesia.

Explanation:

The dosage levels of sedative-hypnotics can be matched with their associated effects as follows:

  • Low dosage: anti-anxiety (GAD, OCD)
  • Low-medium dosage: sedation
  • Medium-high dosage: hypnosis/sleep onset
  • High dosage: general anesthesia

Sedative-hypnotics such as benzodiazepines and barbiturates are commonly used to treat conditions ranging from anxiety and insomnia to serving as an agent in general anesthesia. At low dosages, these drugs primarily exhibit anti-anxiety effects, helpful for conditions like Generalized Anxiety Disorder (GAD) and Obsessive-Compulsive Disorder (OCD). As the dosage increases to a low-medium level, sedative effects become more pronounced, leading to relaxation and decreased inhibitions. Surpassing this, medium-high dosages are associated with hypnosis, promoting sleep onset. Finally, at high dosages, sedative-hypnotics can induce a state of general anesthesia.

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