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Answer :
Final answer:
Given the atraumatic right thigh pain and swelling, weight loss, fatigue, 'onion skin' periosteal reaction, and translocation of chromosome 11 to 22, the most likely diagnosis for this 15-year-old male is Ewing's Sarcoma.
Explanation:
The patient's symptoms of atraumatic right thigh pain and swelling, weight loss, and fatigue, along with the 'onion skin' periosteal reaction seen in the X-ray image and the translocation of chromosome 11 to 22 identified in the biopsy, suggest a diagnosis of Ewing's Sarcoma. Ewing's Sarcoma is a rare type of cancer that affects bones or the tissue surrounding the bones (soft tissue) predominantly seen in children and young adults. Early diagnosis and treatment are pivotal for a favorable prognosis.
Learn more about Ewing's Sarcoma here:
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