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A patient weighing 93 kg is to receive 0.8 mg/kg/day of amphotericin B by continuous 24-hour IV infusion. The product is reconstituted and diluted to 0.1 mg/mL.

What should the rate be in mL/hr to deliver the daily dose?

A. 744
B. 837
C. 930
D. 1023

Answer :

Final answer:

The IV infusion rate for amphotericin B for a patient weighing 93 kg is calculated as 31 mL/hr, which is found by first determining the total daily dose in mg, converting it to the total volume in mL based on the solution's concentration, and then calculating the hourly rate. However, the calculated rate does not match any of the provided options.

Explanation:

To calculate the IV infusion rate in mL/hr for a medication, we need to use the patient's weight and the dosage prescribed by the physician and relate this to the concentration of the medication solution. In this case, a patient weighing 93 kg is to receive 0.8 mg/kg/day of amphotericin B. The product is diluted to 0.1 mg/mL. We first find the total daily dosage in mg and then convert that to the total volume in mL based on the concentration of the solution. Finally, we'll calculate the rate in mL/hr.

  1. Calculate the total daily dose in mg: 93 kg imes 0.8 mg/kg = 74.4 mg/day.
  2. Convert the total daily dose into mL: Since the concentration is 0.1 mg/mL, divide the total daily dose by the concentration to get the volume: 74.4 mg \/ 0.1 mg/mL = 744 mL/day.
  3. Determine the infusion rate in mL/hr: There are 24 hours in a day, so we divide the total volume by 24 to get the hourly rate: 744 mL/day \/ 24 hr/day = 31 mL/hr.

However, none of the provided options match the calculated rate of 31 mL/hr, thus there might be an error in the options provided or in the initial information

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