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Mention one disadvantage of using a Flame Ionizing Detector (FID) over a Thermal Conductivity Detector (TCD) in gas chromatography.

Answer :

One disadvantage of using a Flame Ionization Detector (FID) over a Thermal Conductivity Detector (TCD) in gas chromatography is that the FID requires a flame and a hydrogen-air mixture, which can be potentially hazardous.

The FID is a commonly used detector in gas chromatography, but it has a few disadvantages compared to the TCD. One significant disadvantage is the requirement of a flame and a hydrogen-air mixture. The presence of a flame poses a potential safety risk in the laboratory environment. The use of hydrogen gas also introduces an additional hazard due to its flammability.

In contrast, the TCD does not rely on a flame or flammable gases. It operates based on the difference in thermal conductivity between the carrier gas and the analyte, making it a safer alternative.

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