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Answer :
46.7765 mg/day to 187.106 mg/day is the safe dosage range.
To determine the range of methotrexate dosage in milligrams (mg) that Mr. Doran can safely take, we need to convert his weight from pounds to kilograms.
1 pound is approximately equal to 0.4536 kilograms. Therefore, Mr. Doran's weight in kilograms is:
165 lb * 0.4536 kg/lb = 74.8424 kg (rounded to four decimal places)
Next, we calculate the dosage range based on Mr. Doran's weight. The dosage range is given as 0.625 - 2.5 mg/kg/day. We multiply this range by Mr. Doran's weight in kilograms to obtain the corresponding dosage range for him:
Lower range: 0.625 mg/kg/day * 74.8424 kg = 46.7765 mg/day (rounded to four decimal places)
Upper range: 2.5 mg/kg/day * 74.8424 kg = 187.106 mg/day (rounded to three decimal places)
Therefore, the safe dosage range for Mr. Doran is approximately 46.7765 mg/day to 187.106 mg/day.
It is important to note that the calculated dosage range is based on Mr. Doran's weight and the prescribed dosage range. However, individual factors, such as his specific medical condition, overall health, and any other medications he may be taking, should be considered by his healthcare provider to determine the most appropriate dosage within this range.
This calculation highlights the importance of individualized dosing and the need for healthcare professionals to carefully assess and determine the specific dosage for each patient based on their unique circumstances.
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