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A substance has an LD50 of 336 mg/kg. How many grams of the substance would a 186 kg person have to consume to reach the probable lethal dose?

Answer :

The mass of substance consumed in g to provide a lethal dose is 62.496 g

The substance has an LD50 of 336 mg/kg. We require the number of grams of the substance that a 186 kg person would consume to reach the probable lethal dose.

So, mass of substance consumed = lethal dose × mass of person

lethal dose = 336 mg/kg and mass of person = 186 kg

mass of substance consumed = lethal dose × mass of person

mass of substance consumed = 336 mg/kg × 186 kg

mass of substance consumed = 62496 mg

Converting to g, we have

mass of substance consumed in g = 62496 mg × 1 g/1000 mg = 62.496 g

So, the mass of substance consumed in g to provide a lethal dose is 62.496 g

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