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Which dopamine pathway causes hyperprolactinemia (gynecomastia, galactorrhea, sexual dysfunction, and menstrual abnormalities)?

A. Mesolimbic Pathway
B. Nigrostriatal Pathway
C. Tuberoinfundibular Pathway
D. Mesocortical Pathway

Answer :

Final answer:

The (C) tuberoinfundibular pathway is responsible for causing hyperprolactinemia, leading to symptoms such as gynecomastia and galactorrhea by disrupting the inhibition of prolactin release from the anterior pituitary.

Explanation:

The dopamine pathway that causes hyperprolactinemia, which includes symptoms like gynecomastia, galactorrhea, sexual dysfunction, and menstrual abnormalities, is the tuberoinfundibular pathway. This pathway regulates the secretion of prolactin, a hormone produced by the anterior pituitary gland.

Abnormalities in this dopaminergic pathway can disrupt the inhibition of prolactin release, leading to its excess. Prolactin overproduction can result in the aforementioned symptoms related to hyperprolactinemia.

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