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Answer :
True, a prion is a pathogenic protein that is the cause of degenerative brain diseases.
Prions are infectious agents made up of misfolded proteins that induce the abnormal folding of normal cellular proteins, leading to the formation of harmful aggregates in the brain. These aggregates result in the degeneration of brain tissue, causing various fatal neurological disorders collectively known as transmissible spongiform encephalopathies (TSEs). Some well-known examples of prion diseases include Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease (Bovine Spongiform Encephalopathy) in cattle, and scrapie in sheep.
Prion diseases are unique because they do not involve the transmission of a traditional virus or bacterium. Instead, they arise from the propagation of misfolded proteins that trigger the misfolding of otherwise healthy proteins, creating a chain reaction that ultimately leads to brain damage. The transmission of prions can occur through ingestion, inhalation, or direct contact with contaminated tissue, although some cases are spontaneous or inherited through genetic mutations.
There is currently no cure or effective treatment for prion diseases, and they remain a significant challenge for medical research. Prevention and control measures, such as strict regulations on animal feed and monitoring of livestock, have been implemented to minimize the risk of prion transmission between animals and from animals to humans.
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