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Answer :
Andrew's defective α-receptors on his arterioles make him less responsive to norepinephrine, which might cause chronic hypotension because his arterioles simply won't constrict in response to increased norepinephrine levels.
Arterioles are small blood vessels that connect arteries to capillaries and play a crucial role in regulating blood flow and pressure in the body. They have thick, muscular walls that allow them to constrict or dilate, controlling blood flow to specific organs or tissues. This process, known as vasodilation and vasoconstriction, respectively, helps regulate blood pressure and ensures that organs receive adequate blood supply. Arterioles also contribute to the regulation of systemic vascular resistance, which helps regulate blood volume and pressure within the circulatory system. Abnormalities in arteriole function can contribute to various diseases, including hypertension, heart disease, and stroke.
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