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Answer :
Final answer:
Lotilaner ophthalmic solution treats Demodex blepharitis by inhibiting the neuronal transmission of the mites, leading to paralysis and death. This mechanism is crucial for effectively managing the condition. Lotilaner acts similarly to other neurotoxic agents in its ability to interrupt vital functions in the parasites.
Explanation:
Mechanism of Action of Lotilaner Ophthalmic Solution
Lotilaner ophthalmic solution is used in the treatment of Demodex blepharitis, a condition caused by the infestation of Demodex mites. Unlike conventional treatments, lotilaner works by specifically targeting the neuronal transmission of these mites. The correct mechanism of action includes:
- A. Inhibits GABA channel causing paralysis and death in the mites
- B. Selective serotonin reuptake inhibitor resulting in additional synaptic neurotransmitters in the mites
- C. Inhibits respiration of mites by obstructing respiratory holes causing mite asphyxiation
- D. Blocks beta receptors resulting in decreased respiratory rate and suffocation of the mite
The best answer describing Lotilaner's action is most similar to the inhibition of neuronal transmission (akin to the action of toxins like Botulinum), leading to paralysis and eventual death of the mites. This emphasizes its role in controlling the mite population effectively.
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