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What happens when nitrile reacts with a Grignard reagent?

1) Formation of an alcohol
2) Formation of an amine
3) Formation of an ester
4) Formation of a carboxylic acid

Answer :

Final answer:

The reaction of a nitrile with a Grignard reagent results in the formation of a ketone, following an initial creation of an imine salt and subsequent hydrolysis.

Explanation:

When a nitrile reacts with a Grignard reagent, the outcome of the reaction is the formation of a ketone. The Grignard reagent adds to the electrophilic carbon in the nitrile to form an imine salt. This salt is then hydrolyzed to yield the ketone product. The general mechanism involves the nucleophilic attack by the Grignard reagent on the nitrile to form an imine anion, which after subsequent hydrolysis reactions results in a ketone. It's important to note that while Grignard reagents can react differently with other compounds such as aldehydes, ketones, and esters, in the case of nitriles, the specific product formed is a ketone.

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