Answer :

Final answer:

Neutrophils combat bacterial infection through phagocytosis and the creation of Neutrophil Extracellular Traps (NETs). High neutrophil counts generally indicate presence of an infection or inflammation.

Explanation:

The battle between bacteria and neutrophils, a type of white blood cell involved in the body's innate immunity, is a complex process. Neutrophils, which are capable of phagocytosis, migrate to areas of bacterial infection. They contain granules packed with defensins and hydrolytic enzymes capable of breaking down bacterial cell walls and destroying bacteria. One intriguing mechanism neutrophils use is the creation of Neutrophil Extracellular Traps (NETs). These are meshes of chromatin, associated with antimicrobial granule proteins, which can trap and destroy pathogens.

Neutrophils can also degranulate, releasing toxic molecules into the surrounding tissue to help clear an infection. Neutrophils' activity is reflected in their count, which can fluctuate due to various conditions. High counts suggest infection or inflammation, common in burn patients and others under significant stress, while low counts may indicate drug toxicity or other disorders, increasing susceptibility to infection.

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