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Answer :
The answer to the given question is no, the alcohol in the starting material will not react with the Grignard reagent.
Explanation:
In the given transformation:
ch12 3e d3The reactant is a 1-chlorohexane, which contains a primary halide that will react with the Grignard reagent (3-methyl-2-butanone).In the given starting material, there is an alcohol group attached to the carbon, which means it will not react with the Grignard reagent as it will be more reactive towards its own OH group than the C=O bond of 3-methyl-2-butanone.
Therefore, the correct option is, no, the alcohol in the starting material will not react with the Grignard reagent.
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Final answer:
Grignard reagents will generally react with alcohols to create a intermediate product. The ability for a transformation to occur depends on the context of the reaction system. Main consideration is whether the alcohol will react with the Grignard reagent.
Explanation:
The subject of this question pertains to chemical transformations involving Grignard reagents and alcohols. In general, Grignard reagents, being strong bases, will react with alcohols ranging from primary to tertiary alcohols. This will ultimately lead to the deprotonation of the alcohol creating a magnesium alkoxide intermediate. With regards to the question, whether the transformation can occur or not will depend on the context of your reaction system. If no subsequent reaction steps are included that could form a valid product, it would be challenging to say that the given reaction could occur as is. Overall, the crucial consideration is the reactivity of the alcohol with the Grignard reagent.
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