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Which of the following describes the relationship between pulmonary ventilation and perfusion in the normal standing human being?

A. Ventilation decreases and perfusion increases from the apex to the base of the lung.

B. Ventilation and perfusion both increase from the apex to the base of the lung.

C. Ventilation increases and perfusion decreases from the apex to the base of the lung.

D. Ventilation and perfusion both decrease from the apex to the base of the lung.

Answer :

Ventilation increases and perfusion decreases from the apex to the base of the lung describes the relationship between pulmonary ventilation and perfusion in the normal standing human being. Therefore, the correct option is C.

In a normally standing human body, ventilation (air flow) increases from the top to the bottom of the lungs. Since the base of the lung receives more ventilation than the apex, this is a result of gravitational influence. On the other hand, from the tip of the lung to its base, the perfusion (blood flow) is reduced. Gravity also has an effect on this as it pulls the blood downward, increasing blood flow near the base of the lungs.

Therefore, the correct option is C.

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