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Which of the following are subcortical degenerative dementias?

A. Alzheimer's disease
B. Wilson's disease
C. Parkinson's disease
D. Progressive supranuclear palsy

Answer :

Final answer:

Option (C), Subcortical degenerative dementias include diseases like Parkinson's disease and Progressive supranuclear palsy, which are characterized by issues in movement regulation and dementia, due to degeneration of brain structures below the cortex.

Explanation:

Subcortical degenerative dementias are characterized by the degeneration of structures below the cerebral cortex, often leading to movement difficulties and dementia. Parkinson's disease and Progressive supranuclear palsy both fall into this category.

Parkinson's disease is a neurodegenerative disorder that affects the substantia nigra in the midbrain, resulting in decreased dopamine production.

This deficiency leads to increased rigidity and difficulty in initiating movements, alongside a host of other motor and cognitive symptoms, including dementia in advanced stages.

Progressive supranuclear palsy is a less common neurodegenerative disorder that also causes movement difficulties and dementia.

In contrast, Alzheimer's disease and Wilson's disease are not primarily subcortical degenerative disorders; Alzheimer's primarily affects the cerebral cortex and is the most common cause of general dementia, while Wilson's disease is a genetic disorder that involves copper accumulation affecting the liver and brain.

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