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Nitroprusside dosage: 0.3 mcg/kg/min

Patient weight: 176 lbs

Concentration of nitroprusside: 50 mg/250 ml

Calculate the ml/hr rate.

Answer :

Final answer:

The infusion rate for nitroprusside for a patient weighing 176 lbs, given a dosage of 0.3 mcg/kg/min and a drug concentration of 50 mg/250 ml is approximately 7.2 ml/hr.

Explanation:

The dosage rate of nitroprusside can be calculated by converting the patient's weight from pounds to kilograms, applying the dosage rate, and converting the unit of the drug's concentration. Given the patient's weight as 176 lbs, which is around 79.83 kgs and the desired dosage rate of nitroprusside is 0.3 mcg/kg/min.

The amount of nitroprusside required per hour for this patient would be: 0.3 mcg/kg min * 79.83 kg * 60 min = 1438.94 mcg/hr. Then, we need to convert this dose from mcg to mg since our available concentration is in mg. 1000 mcg = 1 mg, so 1438.94 mcg = 1.43894 mg/hr.

The concentration of the nitroprusside solution is 50 mg in 250 ml, or 0.2 mg/ml. To find the rate in ml/hr, divide the dosage by the concentration: 1.43894 mg/hr / 0.2 mg/ml = 7.1947 ml/hr. So the infusion rate would be around 7.2 ml/hr.

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