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Your task is to synthesize a primary alcohol using a Grignard reagent. Which compound below will react with a Grignard reagent to form the desired primary alcohol?

A. Carbon dioxide
B. Acetone
C. Benzaldehyde

Answer :

The compound that will react with a Grignard reagent to form a primary alcohol is carbon dioxide. Grignard reagents react with carbon dioxide to produce primary alcohols through an addition reaction forming carboxylic acid first, which is then reduced to the primary alcohol during an acid work-up step.

The compound that will react with a Grignard reagent to form a primary alcohol is carbon dioxide.

Grignard reagents are organometallic compounds that contain carbon-magnesium bonds and are typically used in organic syntheses. They generally react with carbon dioxide to produce primary alcohols.

In these reactions, the Grignard reagent adds to the carbon atom of the carbon dioxide, which is connected to two oxygen atoms. This leads to the formation of a carboxylic acid. The carboxylic acid is then reduced to a primary alcohol during an acid work-up step with H3O+.

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