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Answer :
Yunis and Samaha coined the phrase "inclusion body myositis" in 1971.
Vacuoles and filamentous inclusions are a common pathogenic feature of sporadic inclusion body myositis (s-IBM) and hereditary inclusion body myopathies (h-IBM), two different illnesses. They show a wide range of clinical manifestation, age of onset, concomitant disorders, and prognosis when taken as a whole. The subject of this article is s-IBM. The reader is pointed in the direction of other sources for discussion of h-IBM.
In 1971, Yunis and Samaha coined the name "inclusion body myositis" to describe a case of myopathy that phenotypically resembled chronic polymyositis but revealed inclusion bodies and cytoplasmic vacuoles upon muscle biopsy. The disorder has gained more attention in the years since and better histologic techniques have led to an increase in the recognition and reporting of s-IBM.
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"degenerative muscle disease inclusion body myositis" article was created by Mazen M. Dimachkie, M.D. and Richard J. Barohn, M.D.
In their article, they talk about A group of rare diseases known as idiopathic inflammatory myopathies has a lot in common with one another. Dermatomyositis (DM), polymyositis (PM), necrotizing myopathy (NM), and sporadic inclusion body myositis (IBM) are a few examples of these conditions. Chronic proximal leg and distal arm asymmetric muscle weakness is the most common idiopathic inflammatory myopathy after age 50 in inclusion body myositis.
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