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Answer :
Answer: Typhus, Measles, Bubonic plague, Malaria, and Smallpox.
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The introduction of illnesses from the Old World to the Americas was the most disastrous effect of the Columbian exchange. Smallpox, measles, mumps, whooping cough, chickenpox, typhus, and influenza were among the deadly pathogens.
In the meantime, the domestication of herd animals in Asia and Africa brought forth new diseases that were carried by cattle, sheep, pigs, and poultry. These illnesses, such as smallpox, measles, mumps, whooping cough, influenza, chicken pox, and typhus, were unintentionally brought to the Americas by sailors shortly after 1492. The spread of disease, rather than the proliferation of firearms, was the Columbian Exchange's most disastrous outcome. Up to 95% of all Americans are thought to have died in the years after the European invasion.
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