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Answer :
There were three different treatments: erythropoietin, darbepoetin, and no treatment. This selection exemplifies the principle of randomization principle.
What is a treatment?
In experiments, the word treatment refers to the use of a specific medicine, therapy, or condition that is controlled by the research to test the effect of the treatment on subjects. For example, if the researcher wants to find out the ideal amount of water for a plant to grow, the treatment would be the amount of water.
In the case presented, there are three treatments:
- Erythropoietin (epo) three times a week.
- Darbepoetin once a week for several weeks.
- No treatment.
What principle of experimental design does that address?
Randomization is the principle applied because the subjects are selected randomly for each of the groups and this reduces bias.
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Final answer:
There were three different treatments studied - erythropoietin (EPO) injections, darbepoetin injections, and no treatment. This applied the randomization principle of experimental design. Blood-building drugs like EPO seem to aid brain development in premature babies, leading to improved intelligence, language, and memory skills.
Explanation:
In the study described, there were three different treatments applied to the babies - injections of erythropoietin (EPO) three times a week, darbepoetin once a week, and no treatment. This addresses the principle of experimental design called randomization where each participant is randomly assigned to a treatment group, reducing potential bias and ensuring that the results are caused by the treatments and not by any other factor.
EPO is a hormone that stimulates the formation of red blood cells, crucial for carrying oxygen to different parts of the body. Synthetic EPO, like the one administered in this study, can stimulate this production when injected, which in turn could benefit the development of crucial organs such as the brain. Improved brain development can lead to improved intelligence, language, and memory skills, as observed in this study.
The positive results observed in the babies receiving blood-building drugs point to the potential of these treatments in aiding the development of babies born prematurely, however, further research is always necessary to confirm these kinds of results and to investigate any potential long-term effects of treatment.
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