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Which dopamine pathway is associated with positive symptoms of schizophrenia?

1) Mesolimbic pathway
2) Mesocortical pathway
3) Nigrostriatal pathway
4) Tuberoinfundibular pathway

Answer :

Final answer:

The mesolimbic pathway is associated with the positive symptoms of schizophrenia. Overactivity in this pathway leads to symptoms like hallucinations and delusions, and is targeted by antipsychotic medications. option a is answer

Explanation:

The dopamine pathway associated with positive symptoms of schizophrenia is the mesolimbic pathway. This pathway starts with dopaminergic cell bodies in the ventral tegmental area (VTA) that extend axons to the nucleus accumbens and other limbic structures. Positive symptoms of schizophrenia, which include hallucinations and delusions, are thought to be linked to overactivity in this pathway.

Antipsychotic medications, which act as dopamine receptor antagonists, can help to alleviate these symptoms by reducing dopamine function within the mesolimbic pathway. This underscores the role of dopamine in the manifestation of positive symptoms and supports the dopamine hypothesis of schizophrenia. option a is answer

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