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Choline is a quaternary ammonium compound with a positive charge on the nitrogen.
Choline is a quaternary ammonium compound, meaning it has four substituent groups attached to the nitrogen atom. The nitrogen atom in choline carries a positive charge due to the presence of four alkyl or aryl groups attached to it. This positive charge is a result of the nitrogen atom having donated its lone pair of electrons to form bonds with the substituent groups. The positive charge on the nitrogen makes choline a cationic compound, and it plays important roles in various biological processes as a precursor for the neurotransmitter acetylcholine and as a component of cell membranes.
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Choline is a quaternary ammonium compound with a positive charge on the nitrogen. Its structural formula is `(CH3)3N+CH2CH2OH`.
Choline is an essential nutrient required by the human body in small amounts for a variety of physiological functions, including liver function, healthy brain development, nerve function, muscle movement, and metabolism.
The primary role of choline is to contribute to the structural integrity of the cell membrane, including those in the brain, where it is a precursor to the neurotransmitter acetylcholine. It is also involved in lipid metabolism and transport, particularly in the liver, and aids in the transport of lipids and cholesterol in the blood. Choline plays a crucial role in fetal and infant brain development. Pregnant women and nursing mothers should take in enough choline to help their babies' brains develop and function properly. Choline deficiency has been linked to liver disease, cardiovascular disease, cognitive decline, and neurological disorders, including Alzheimer's and dementia.
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