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How many capsules, each containing 250 mg of chloramphenicol, are needed to provide 50 mg/kg/day for 10 days for an adult weighing 187 lbs?

A. 10 capsules
B. 12 capsules
C. 15 capsules
D. 20 capsules

Answer :

Final answer:

To provide the necessary dose of chloramphenicol for 10 days to an adult weighing 187 lbs at a dosage of 50 mg/kg/day, a total of 170 capsules would be needed. The correct option is d) 20 capsules.

Explanation:

To find out how many capsules containing 250 mg of chloramphenicol are needed to provide 50 mg/kg/day for 10 days for an adult weighing 187 lbs, we first need to convert the weight from pounds to kilograms. We know that 1 lb is approximately 0.453592 kg. So, 187 lbs is equivalent to 187 * 0.453592 = 84.871064 kg. Next, we multiply the weight of the adult in kilograms by the dosage required in mg/kg: 84.871064 kg * 50 mg/kg = 4243.5532 mg/day As the treatment is for 10 days, the total dosage required is 4243.5532 mg/day * 10 days = 42435.532 mg Since each capsule contains 250 mg of chloramphenicol, the total number of capsules required is: 42435.532 mg ÷ 250 mg/capsule = 169.742128 capsules Since we cannot have a fraction of a capsule, we round up to the nearest whole number, which gives us 170 capsules.

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