A nurse is reinforcing teaching with a client who has a prescription for alendronate. Which of the following client responses indicates to the nurse an understanding of the teaching?

A. "I will take the medication with my breakfast."
B. "I will take the medication with 1 tbsp of an antacid."
C. "I will lie down for 30 min after taking the medication."
D. "I will take the medication with 8 oz of water."

The nurse would know the client understands the teaching if the client plans to take alendronate with 8 oz of water. This method ensures proper absorption and reduces the risk of gastrointestinal irritation. Alendronate should not be taken with food, beverages, or antacids, and the patient should remain upright for at least 30 minutes post-ingestion.

Explanation:

The correct answer to the question is D: "I will take the medication with 8 oz of water." Alendronate should be taken with a full glass (6-8 ounces) of plain water, at least 30 minutes before having any food, beverages, or other medications to ensure adequate absorption and to reduce the risk of esophageal irritation. Clients should remain upright for at least 30 minutes after taking it. Taking alendronate with breakfast, antacids, or lying down soon after taking it can result in inadequate absorption of the medication or increase the risk of side effects.

Regarding antacids, it's important to note that they have side effects such as constipation or diarrhea depending on their content. Taking alendronate with antacids is not advisable. Additionally, acid-base titration is a laboratory method used to determine the concentration of an acid or base in a solution which is not directly related to the administration of alendronate but is a fundamental concept in chemistry.