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A client weighing 114 lb is prescribed trastuzumab 4 mg/kg IV infusion over the next 90 minutes. After reconstitution of the medication, the multidose solution contains 21 mg/mL. How many mL should the nurse administer to the client?

Answer :

Final answer:

To administer the correct dose of trastuzumab to a 114 lb client, the nurse needs to calculate the client's weight in kilograms, determine the total dose required, and divide this by the solution's concentration, resulting in the administration of approximately 9.85 mL of the solution.

Explanation:

The question involves calculating the volume of trastuzumab medication required for a client weighing 114 lb, where the medication is prescribed at a dosage of 4 mg/kg.

First, the client's weight must be converted from pounds to kilograms. Since 1 pound is equal to 0.453592 kilograms, the client's weight in kilograms is 114 lb × 0.453592 kg/lb = 51.71 kg (approximately).

The total dose required is then calculated by multiplying the weight in kilograms by the prescribed mg/kg dosage, yielding 51.71 kg × 4 mg/kg = 206.84 mg.

Given that the reconstituted solution's concentration is 21 mg/mL, the volume of the solution required is calculated by dividing the total dose by the solution concentration, resulting in 206.84 mg ÷ 21 mg/mL = 9.85 mL.

Therefore, the nurse should administer approximately 9.85 mL of the solution to the client.

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