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Answer :
Ordered: Dobutamine 500 mg in 250 mL to infuse at 75 mg/h for a patient weighing 176 lb . The maximum safe dosage of dobutamine is 40 mcg/kg/min . If this is a safe dose, calculate the flow rate 37.5 mL/h.
First, convert the patient's weight from pounds to kilograms: 176 lb = 80 kg.
Next, determine the maximum safe dosage: 40 mcg/kg/min for an 80 kg patient corresponds to:
- (40 mcg/kg/min) x (80 kg) = 3200 mcg/min
Convert mcg to mg to match the infusion rate units:
- 3200 mcg/min x (1 mg/1000 mcg) = 3.2 mg/min
Now, convert the infusion rate from mg/h to mg/min:
- 75 mg/h ÷ 60 min/h = 1.25 mg/min
- Since 1.25 mg/min is less than 3.2 mg/min, the infusion rate is safe.
Finally, calculate the flow rate of the infusion:
The infusion is prepared at 500 mg in 250 mL. Since the ordered rate is 75 mg/h, determine how many mL/h:
- (250 mL/500 mg) x (75 mg/h) = 37.5 mL/h
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