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Answer :
Final answer:
The infusion rate of Aggrastat for a patient weighing 87 kg, given the drug concentration of 14.6 mg in 114 ml and a prescribed administration rate of 1 mcg/kg/hr, is approximately 0.7 mL/hr.
Explanation:
This is a question of medicine, specifically pharmacology. The calculation is about determining the correct infusion rate for a medication called Aggrastat. This is a kind of problem often encountered in medication administration in medical or nursing practice.
First, we need to know how many mcg of Aggrastat are in 1 mL. The original concentration is 14.6 mg in 114 mL. Given that 1 mg = 1000 mcg, this translates to 14600 mcg. Hence, the mcg per mL of Aggrastat is 14600/114 = approximately 128.1 mcg/mL.
The prescribed rate of administration is 1 mcg/kg/hr. For an 87-kg patient, the hourly dosage would be 1 mcg/kg/hr * 87 kg = 87 mcg/hr. Because our concentration is about 128.1 mcg/mL, this means we need to administer 87 mcg/hr / 128.1 mcg/mL = approximately 0.679 mL/hr of the medication. In other words, you will set the pump to infuse at about 0.7 mL/hr.
In conclusion, for a patient who weighs 87 kg, the infusion rate of Aggrastat at 14.6 mg in 114 mL to be infused at 1 mcg/kg/hr is 0.7 mL/hr when rounded to the nearest tenth.
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