Answer :

Final answer:

The main pathological feature of degenerative joint disease is the progressive erosion and loss of the articular cartilage in synovial joints, leading to increased bone pressure, pain, inflammation and joint stiffness.

Explanation:

The chief pathologic feature of degenerative joint disease, also known as osteoarthritis, is the erosion and loss of the articular cartilage that covers the surfaces of bones in synovial joints. This process is often associated with aging, joint wear and tear, and may be accelerated by risk factors such as physical labor, certain sports activities, joint injury, and being overweight. As the articular cartilage deteriorates, more pressure is placed on the bones causing pain and inflammation. The affected joint responds by increasing production of the lubricating synovial fluid, leading to joint cavity swelling and stiffness. Ultimately, the bone tissue under the damaged cartilage thickens, making the joint surface rough or uneven which results in further pain and inflammation during joint movements.

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