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What kind of precautions need to be taken when working with Grignard reagents?

Additionally, which of the following types of functional groups react with Grignard reagents: alkenes, ter...

Answer :

Final answer:

When working with Grignard reagents, it is important to take precautions such as handling them in a dry and inert atmosphere, avoiding exposure to moisture and oxygen, and avoiding contact with flammable or reactive materials. Grignard reagents primarily react with carbonyl compounds like aldehydes, ketones, esters, and carboxylic acids. They can also react with epoxides, nitriles, and certain halides.

Explanation:

Precautions when working with Grignard reagents:

  • Handle Grignard reagents in a dry and inert atmosphere, such as a glovebox or under a nitrogen atmosphere.
  • Avoid exposure to moisture and oxygen by using dry glassware and solvents.
  • Avoid contact with flammable or reactive materials.

Functional groups that react with Grignard reagents:

  • Carbonyl compounds: aldehydes, ketones, esters, and carboxylic acids.
  • Epoxides
  • Nitriles
  • Certain halides

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