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Answer :
Final answer:
Polychromasia, observed on a peripheral blood smear, is best explained by increased reticulocytes, signifying an elevated production of red blood cells in response to conditions like anemia or blood loss.
Explanation:
The observation that would best explain why a peripheral blood smear is exhibiting polychromasia is increased reticulocytes. Polychromasia in a blood smear refers to the presence of immature red blood cells (RBCs), also known as reticulocytes. These reticulocytes are released into the bloodstream when the body needs to produce more RBCs quickly, for example, in response to anemia, blood loss, or conditions that destroy RBCs such as hemolytic anemia.
Polychromasia indicates increased red cell production by the bone marrow. When mature RBCs are stained and examined under a microscope, they usually have a uniform light red color. However, reticulocytes, being younger, contain RNA and hence stain differently resulting in a multicolored (or polychromatic) appearance on a peripheral blood smear.
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Complete question version:
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Which of the following observations would best explain why a peripheral blood smear is exhibiting polychromasia?
A. hgb concentration
B. increased reticulocytes
C. decreased hematocrit
D. decreased RBCs
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