Answer :

Despite being a slowly progressive, debilitating disorder that, after 10-15 years of diagnosis, leaves 37% of patients in need of a wheelchair and another 38% in need of a cane, inclusion body myositis is not linked to an elevated death rate, according to large observational studies.

The varied group of diseases known as the idiopathic inflammatory myopathies includes inclusion body myositis (IBM), polymyositis (PM), dermatomyositis (DM), and other rare myopathies. Although these disorders have many clinical traits, they are distinct in terms of histopathology and clinical features. IBM, the most common kind of acquired inflammatory muscle disease, affects adults over 50 and is characterised by gradually worsening muscular atrophy and weakness that commonly occurs asymmetrically in both proximal and distal muscle groups. Unlike DM and PM, IBM frequently demonstrates immunotherapy resistance. Despite the fact that corticosteroids have not been the subject of randomised controlled research, the general consensus is that they are useless. Intravenous immunoglobulin may slow the progression of a number of illnesses, but its durability is uncertain.

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