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Which of the following statements explains the amazing array of potential antibodies to the variety of possible antigens?
a. Genetic recombination and somatic hypermutation in B cells.
b. Clonal selection and expansion of T cells.
c. Activation of macrophages in response to antigens.
d. Differentiation of memory cells during the immune response.

Answer :

Final answer:

The correct option is a. Genetic recombination and somatic hypermutation in B cells. The variety of potential antibodies is due to genetic recombination and somatic hypermutation in B cells, which through clonal selection and expansion lead to a diverse range of antibodies with unique antigen-binding sites.

Explanation:

The correct option is a. Genetic recombination and somatic hypermutation in B cells. The amazing array of potential antibodies to the variety of possible antigens is explained by: a. Genetic recombination and somatic hypermutation in B cells. This is because each B-lymphocyte becomes genetically programmed to make a unique antibody molecule through a process called gene translocation.

Specific molecules of that antibody are placed on the cell's surface as a B-cell receptor. When an antigen with a corresponding epitope shape activates the B-lymphocyte, it leads to clonal selection and clonal expansion. Activated B-lymphocytes then proliferate into a large clone of identical B-lymphocytes, and this can involve somatic hypermutation.

Which increases the diversity of the antigen-binding sites of the antibodies produced. Lastly, the B-lymphocytes differentiate into plasma cells, which are essentially antibody factories secreted fitting the original epitope, and some differentiate into B-memory cells for a more rapid response upon re-exposure to the same antigen.

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